Description: Tolvaptan works by blocking the effects of vasopressin, a hormone that causes water retention in the kidneys. Vasopressin increases water reabsorption in the kidneys, causing fluid retention. By blocking vasopressin, less water is retained in the kidneys and less fluid is retained in the body.

People taking medications that increase their risk of developing liver problems should not take Tolvaptan. People with severe liver disease should not take Tolvaptan.